The Genetic Basis of Haematological Cancers 1st Edition

June 28, 2017

Written by a team of international experts, this book provides an authoritative overview and practical guide to the molecular biology and genetic basis of haematologic cancers including leukemia. Focusing on the importance of cytogenetics and related assays, both as diagnostic tools and as a basis for translational research, this is an invaluable guide for basic and clinical researchers with an interest in medical genetics and haemato-oncology.

The Genetic Basis of Haematological Cancers reviews the etiology and significance of genetic and epigenetic defects that occur in malignancies of the haematopoietic system. Some of these chromosomal and molecular aberrations are well established and already embedded in clinical management, while many others have only recently come to light as a result of advances in genomic technology and functional investigation. The book includes seven chapters written by clinical and academic leaders in the field, organised according to haematological malignancy sub-type. Each chapter includes a background on disease pathology and the genetic abnormalities most commonly associated with the condition. Authors present in-depth discussions outlining the biological significance of these lesions in pathogenesis and progression, and their use in diagnosis and monitoring response to therapy. The current or potential role of specific abnormalities as novel therapeutic targets is also discussed. There is also a full colour section containing original FISH, microarrays and immunostaining images.

 

 

Free Download

Format : PDF

Size : 6.5 MB

PDF Quality : Great

Number of Pages : 384

Download Now

 

Do you like this book ? Was it useful for you ?
If so , please purchase an original copy from the link below :

Share it :Share on Facebook0Share on Google+0Share on LinkedIn0Tweet about this on Twitter

No Comments

Leave a Reply

Your email address will not be published. Required fields are marked *

Medsmart Books